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Aug 19, 2015

Sebastian Sarvari has published in the online edition of the European Heart Journal - Cardiovascular Imaging


 

Sebastian Sarvari, PhD, MD, has published in the online edition of the renowed European Heart Journal - Cardiovascular Imaging. The article was published on July 27th and is titled "Strain echocardiographic assessment of left atrial function predicts recurrence of atrial fibrillation."

The aim of this study was to see if a dispersed left atrial contraction pattern was related to atrial fibrillation in patients with normal left ventricular function, and normal or mildly enlarged left atrium. The study included 61 patients.

Co-authors are Haugaa KH, Stokke TM, Ansari HZ, Leren IS, Hegbom F, Smiseth OA and Edvardsen T.

Posted by: Anonymous

ABSTRACT

AIMS:

We evaluated if a dispersed left atrial (LA) contraction pattern was related to atrial fibrillation (AF) in patients with normal left ventricular (LV) function, and normal or mildly enlarged left atrium.

METHODS AND RESULTS:

We included 61 patients with paroxysmal AF (PAF). Of these, 30 had not while 31 had recurrence of AF after radiofrequency ablation (RFA). Twenty healthy individuals were included for comparison. Echocardiography was performed in patients in sinus rhythm the day before RFA. LA volume was calculated. Peak negative longitudinal strain was assessed in 18 LA segments during atrial systole. Contraction duration in 18 LA segments was measured as the time from peak of the P wave on electrocardiogram to maximum myocardial shortening in each segment. The standard deviation of contraction durations was defined as LA mechanical dispersion (LA MD). LA size was rather preserved in patients with PAF (LA volume 25 ± 10 mL/m2). LA MD was more pronounced in patients with recurrence of AF after RFA compared with those without recurrence and controls (38 ± 14 ms vs. 30 ± 12 ms vs. 16 ± 8 ms, both P < 0.001). LA MD was a predictor of PAF [OR 7.84 (95%CI 2.15-28.7), P < 0.01, per 10 ms increase] adjusted for age, LA volume, e', and LA function. LA function by strain was reduced in both patients with and without recurrent AF after RFA compared with controls (-14 ± 4% vs. -16 ± 3% vs. -19 ± 2%, both P < 0.05).

CONCLUSION:

LA MD was pronounced, and LA deformation was reduced in patients with PAF with apparently normal LV structure and function, and normal or mildly enlarged LA. LA MD may be useful as a predictor of AF recurrence after RFA.

© The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology.

 

Strain echocardiographic assessment of left atrial function predicts recurrence of atrial fibrillation.
Sarvari SI, Haugaa KH, Stokke TM, Ansari HZ, Leren IS, Hegbom F, Smiseth OA, Edvardsen T 
Eur Heart J Cardiovasc Imaging. 2015 Jul 27. [Epub ahead of print]
pii: jev185
PMID: 26219297

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